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Thymosin Beta-4

THE FULL-SPECTRUM HEALER

TB4, Tβ4, Thymosin β-4

Thymosin Beta-4 is a 43-amino-acid peptide that your body naturally produces to orchestrate healing. It promotes blood vessel formation, reduces scarring (fibrosis), and protects tissues from damage. It's particularly valued for heart recovery after injury and reducing inflammation throughout the body. TB-500 is a fragment of this full-length peptide.

Thymosin Beta-4
Thymosin Beta-4
Thymosin Beta-4

Thymosin Beta-4 Evidence Snapshot

How these guides are reviewed
REGULATORY STATUS

Not FDA approved · research use only

DOSING GUIDANCE

Reviewed by our clinical team

LINKED EVIDENCE

1 research sources

CONTENT UPDATED

Aug 28, 2026

Dose and schedule recommendations shown below come from The Peptide App Clinical Team. Research links are provided so readers can inspect the supporting evidence directly. Review the sources.

Quick Answers About Thymosin Beta-4

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Is Thymosin Beta-4 FDA approved?

No. This profile records Thymosin Beta-4 as not FDA approved and for research use only.

MORE CONTEXT ›

Review the regulatory and source details on this page for the current context.

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What dose does The Peptide App Clinical Team recommend for Thymosin Beta-4?

Dose: 300 mcg daily for 2 weeks (Ac-SDKP fragment).

MORE CONTEXT ›

Schedule: daily. Cycle: 2 weeks on, 6 weeks off. This is clinical-team guidance for reference and does not replace individualized instructions from a licensed clinician.

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What research supports this Thymosin Beta-4 guide?

This guide links to 1 curated or current research sources.

MORE CONTEXT ›

Open the research section to inspect the source titles, publication details, study types, and available abstracts directly.

Studied Effects & Mechanisms

Anti-Fibrotic Action

Ac-SDKP fragment suppresses TGF-β1 signaling to reduce scarring and fibrosis

Cardiac Protection

AGES fragment protects heart cells and promotes cardiomyocyte survival after injury

Antioxidant Defense

Tβ4(1-15) fragment increases protective Bcl-2/Bax ratio and activates survival pathways

Angiogenesis

Promotes formation of new blood vessels to support tissue repair

People recovering from heart issues or cardiac injury
Those with fibrotic conditions (lung, liver, kidney)
Anyone dealing with chronic inflammation
Post-surgery recovery support
Athletes needing full-body tissue repair

Thymosin Beta-4 Research

Live research temporarily unavailable

The live research feed did not return papers for this page. The curated references below remain available for crawlable source context.