Is Sigumir FDA approved?
No. This profile records Sigumir as not FDA approved and for research use only.
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Review the regulatory and source details on this page for the current context.
THE JOINT REBUILDER
Cartilage Peptide Complex
Sigumir is a cartilage-derived bioregulator peptide that supports joint health and cartilage regeneration. It works by influencing gene expression in chondrocytes (cartilage cells) to boost collagen and proteoglycan production while reducing inflammatory enzymes that break down cartilage. It's particularly useful for osteoarthritis, joint injuries, and age-related cartilage degeneration.
Not FDA approved · research use only
Reviewed by our clinical team
1 research sources
May 8, 2026
Dose and schedule recommendations shown below come from The Peptide App Clinical Team. Research links are provided so readers can inspect the supporting evidence directly. Review the sources.
No. This profile records Sigumir as not FDA approved and for research use only.
Review the regulatory and source details on this page for the current context.
Dose: 10 mg daily (oral or subcutaneous).
Schedule: daily. Cycle: 10-30 days on, 4 months off. This is clinical-team guidance for reference and does not replace individualized instructions from a licensed clinician.
This guide links to 1 curated or current research sources.
Open the research section to inspect the source titles, publication details, study types, and available abstracts directly.
Upregulates type II collagen and aggrecan genes
Suppresses enzymes that break down cartilage
Increases IGF-1 and TGF-β for cartilage repair
Enhances synovial fluid and lubricin production
The live research feed did not return papers for this page. The curated references below remain available for crawlable source context.